What Is Progeline? Origin & INCI Name
Progeline is a biomimetic peptide with the INCI name Glycerin (and) Water (and) Dextran (and) Trifluoroacetyl Tripeptide-2. It’s derived from elafin, which is a protein that naturally occurs in our skin. Elafin is produced by our cells as a protease inhibitor, which means that it stops enzymes from breaking down proteins. In other words, it helps to keep our skin cells intact for a longer period of time.
How Does Progeline Work? The Claims
Progeline is supposed to work by inhibiting the activity of elastase and collagenase, two enzymes that are responsible for breaking down elastin and collagen. Elastin is a protein that gives our skin its elasticity, while collagen is a protein that gives our skin its strength and structure.
By inhibiting the activity of these enzymes, progeline can help to prevent the breakdown of elastin and collagen, which in turn can help to reduce the appearance of wrinkles and fine lines.
Another thing is that progeline can reduce the production of progerin. Progerin is a protein that speeds up the aging process. So, by reducing its synthesis in your body, progeline can help to slow down the aging process and keep your skin looking young and healthy for longer.
What Are the Benefits of Progeline?
Assuming the above is true, progeline can offer a lot of benefits for your skin. For one, it can help to reduce the appearance of wrinkles and fine lines. It can also help to firm and tighten your skin, giving you a more youthful appearance. Additionally, progeline can help to protect your skin from damage caused by UV radiation and other environmental stressors.
Is Progeline Effective? What Experts Doubt
Now that we know how progeline works in theory, let’s take a look at whether or not it’s actually effective. Unfortunately, there is no concrete evidence that progeline can do everything that it claims to do. Here are the doubts expressed by experts:
- Third-party studies haven’t confirmed its efficacy. In fact, few studies have been done on progeline at all, and they mostly suggest it doesn’t work.
- It’s unclear if progeline can penetrate the skin. While the science behind peptides is logically sound, there’s no guarantee that progeline can actually penetrate the skin and reach the target cells. It’s likely that the peptide is eliminated by the body instead of being incorporated into the skin cells.
- The long-term effects of progeline are unknown. We don’t know if progeline is safe to use in the long run, or if it can cause any adverse effects.
- While it might actually slow down the aging process, progeline is not a magic bullet that can instantly remove all signs of aging from your skin. Past damage is irreversible, so progeline can only help to prevent future damage.
So, what do we make of all this? Is progeline effective or not? At this point, it’s still too early to tell. Progeline shows a lot of promise, but there is still more research to be done before we can say for sure. In the meantime, how do we explain the 92% satisfaction rate reported by customers who have used progeline-based products?
Why Progeline Seems to Work
Let’s say you’re shopping for a new anti-aging product, and you come across two options. One is progeline-based, and the other is not. Which one are you going to choose? It doesn’t matter, because both products will probably work the same.
The fact is, most anti-aging products on the market today don’t actually do anything to slow down the aging process. Instead, they rely on moisturizing ingredients to improve the appearance of your skin. And what’s the moisturizing agent in progeline? Glycerin.
Glycerin can certainly help to improve the appearance of your skin. It can make your skin look plumper and smoother, and it can also help to reduce the appearance of fine lines and wrinkles. But glycerin is found in many other products, not just progeline-based ones. So, it’s likely that progeline isn’t doing anything special here.
Are There Any Proven Anti-Aging Ingredients?
Yes, there are a few ingredients that have been proven to be effective at slowing down the aging process. For example, retinoids (vitamin A derivatives) have been shown to stimulate collagen production, which can help to reduce the appearance of wrinkles and fine lines. Other ingredients like niacinamide (vitamin B) and coenzyme Q10 (an antioxidant) can also help to protect your skin from damage and improve its overall appearance.
The Bottom Line
Progeline shows a lot of promise, but there is still more research to be done before we can say for sure if it’s effective. In the meantime, you might want to stick to proven anti-aging ingredients like retinoids, niacinamide, and coenzyme Q10.
Do you have any experience with progeline? Let us know in the comments below!